Bipolar disorder is a condition by which the sufferer has episodes of mania and/or depression. If this is misdiagnosed as major depression, the patient is usually given an antidepressant such as Zoloft. Zoloft belongs to the SSRI drug class, under antidepressants. However, a warning has been issued by the FDA regarding the use of Zoloft in individuals with bipolar disorder as this may yield undesirable effects. Misdiagnosis is not just one of the common problems in the misuse of antidepressants because the absence of psychiatric diagnoses increases antidepressant use as well.
Action of Antidepressants
Antidepressants especially those under the SSRI class, work by limiting the reuptake of serotonin.
Normal levels of serotonin in the brain are then maintained by way of this. Serotonin is the neurotransmitter that has a major effect on our mood. In the case of depression, low levels of serotonin are found in the brain. In cases otherwise, symptoms of panic or anxiety are observed in an individual.What Happens When it?s Used in Bipolar Disorder?
An individual suffering from this condition may be depressed and then hyperactive, or vice versa. Drugs used in management for this disorder are mood stabilizers including lithium and anticonvulsants. Antidepressants were given as an adjunct therapy to mood stabilizers before. The reason for this is that antidepressants might increase the patient?s risk of developing mania to depression in rapid cycles. However, future studies have proven that antidepressants are no longer effective in managing bipolar disorder even with mood stabilizers. Also, atypical antipsychotic medications are used in the management of bipolar disorder but other medications should be taken together with the drug to avoid fatal side effects. Most drugs, if not all, have side effects. As an example, the antidepressant Zoloft is associated with Zoloft birth defects, which is why the FDA issued a warning regarding the drug as well as a warning on it not being used as a bipolar medication. There are other management for Bipolar disorder that doesn?t concern medications such as psychotherapy but it usually takes a long time to see the effect.
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